| IGrow Digital | |
| IIS Group | Western Cape |
| iKabot | Western Cape |
| iKhokha | KwaZulu-Natal |
| iLead Online | Gauteng |
| iLearn | Gauteng |
| iLembe Technologies | KwaZulu-Natal |
| iLite | Western Cape |
| Imafin | |
| Imagine ISP | Gauteng |
| Impact Amplifier | |
| Imperative Technology | Gauteng |
| Impero Consulting | Gauteng |
| Impression Management | KwaZulu-Natal |
| improWEB | Gauteng |
| Impulsum (Pty) Ltd | Western Cape |
| Imvelo Ventures | Gauteng |
| In Touch With The World | Gauteng |
| Inbounder (Pty) Ltd | |
| Incasu (Pty) Ltd | Gauteng |
| Ince Communications | Gauteng |
| Incus Data | Gauteng |
| Independent Communications Authority of South Africa | |
| Industrial Data Xchange | Gauteng |
| Industrial Development Corporation | Gauteng |
| Inessoft | Gauteng |
| Inext ISP | Northern Cape |
| InfiNET IT | KwaZulu-Natal |
| InfoGro | Gauteng |
| Information Systems Engineering (Pty) Ltd | Gauteng |
| Information Technology Engineering (Pty) Ltd | Western Cape |
| InfoStream Technologies | Gauteng |
| Infovate | Gauteng |
| Infracomm Technology Solutions | KwaZulu-Natal |
| Ingran | Gauteng |
| Initiative SA Investments 110 (Pty) Ltd | Gauteng |
| Injini | Western Cape |
| Ink 4 U | Gauteng |
| Innervation Pan African Payments (Pty) Ltd | Gauteng |
| Innovative Stellenbosch Business Park | Western Cape |
| Insite Labs | Eastern Cape |
| Insite Solutions | Western Cape |
| Insly Host (Pty) Ltd | Gauteng |
| Inspire-IT | |
| Inspired Web | |
| Institute of Information Technology Professionals South Africa | Gauteng |
| Instrotech | Gauteng |
| IntDev | Limpopo |
| Integral Systems | Gauteng |
| Integrat (Pty) Ltd | Gauteng |