| BrandXtreme | Gauteng |
| Brayfoil Technologies | Gauteng |
| Breakpoint | Western Cape |
| Breeze Website Designers | Gauteng |
| Bright On Capital | |
| Broadband Infraco | Gauteng |
| BSG Africa (Pty) Ltd | Western Cape |
| BSolve | Western Cape |
| BT Games | Gauteng |
| BTec Consulting | KwaZulu-Natal |
| Buffalo City College | |
| BUI | Gauteng |
| Build Marketing | |
| Bullion IT | Gauteng |
| Burst Digital | |
| Busii | Western Cape |
| Business Engage | |
| Business Engineering (Pty) Ltd | Gauteng |
| BusinessTech | Gauteng |
| BustQue | Gauteng |
| BVI Network Security Services (Pty) Ltd | Gauteng |
| Bweb (Pty) Ltd | |
| Bydrae (Pty) Ltd | Western Cape |
| Byte Orbit | Western Cape |
| Bytespark | Western Cape |
| C-Boards | Gauteng |
| C-Page | Gauteng |
| C2I2 Systems | Western Cape |
| C2KIT Computer Supplies (Pty) Ltd | |
| Cable Applications | Gauteng |
| CaCell | Gauteng |
| CAD Corporation | Gauteng |
| CAD4All Software CC | Western Cape |
| Cagro Consulting Services | Gauteng |
| Camara Consulting | Western Cape |
| Cameraman CCTV | Gauteng |
| Camsoft Solutions | Western Cape |
| Canon South Africa (Pty) Ltd | Gauteng |
| Cantaloupe Digital | Gauteng |
| Cape Health Tech Week | Western Cape |
| Cape Higher Education Consortium | Western Cape |
| Cape Innovation & Technology Initiative | Western Cape |
| Cape Peninsula University of Technology | Western Cape |
| Cape Peninsula University of Technology - Informatics and Design | Western Cape |
| CapeConnectInternet | Western Cape |
| CapeSoft | Western Cape |
| CapeTel | Western Cape |
| CapeWeb | Western Cape |
| Capital Appreciation Ltd | |
| Capital Design | Gauteng |