| Borax | Barcelona |
| Borneo Analytics | Gipuzkoa |
| Boston Tech, S.L. | Madrid |
| Botigues.cat | Girona |
| Bouge, S.A. | Madrid |
| Box2box, S.L. | Madrid |
| Boxfish Studio, S.L. | Madrid |
| BPM&SOA Solutions | Madrid |
| Brain Hardware, S.L. | Madrid |
| Bravent | Madrid |
| Bredax | Barcelona |
| Brickken PFP, S.L. | Barcelona |
| Brielco Componentes y Artículos Electrónicos | Jaén |
| Brill Pharma, S.L. | Barcelona |
| Brother Iberia, S.L.U. | Madrid |
| Bryte | Barcelona |
| BSM Informática, S.L. | Gipuzkoa |
| BTESA Broad Telecom S.A. | Madrid |
| BTODigital | Málaga |
| Bulegoak Soluciones Tecnológicas | Gipuzkoa |
| Bullhost | Biscay |
| Business Factory Auto | Pontevedra |
| butic | Madrid |
| Butler Scientifics, S.L. | |
| Byom! | |
| Bytemaster | Barcelona |
| BytePC | Madrid |
| C.B.D. S.A. Dirac | Valencia |
| C3S Business School | |
| Cabify | Madrid |
| Cableados Jecri, S.L. | Barcelona |
| Cablecom | Barcelona |
| CableData Telecom | Málaga |
| Cablematic Dos Mil, S.L.U. | Barcelona |
| Cables de Comunicaciones Zaragoza, S.L. | Zaragoza |
| Cables RCT | Zaragoza |
| Cables y Eslingas, S.L.U. | Barcelona |
| Cabletronic | Barcelona |
| Cadtec Services, S.A. | Madrid |
| Cadtech Ibérica, S.A. | Barcelona |
| Cadvision, S.L. | Biscay |
| CAEsoft | Madrid |
| Cafler | Barcelona |
| CAI Sistemas Informáticos, S.L. | Pontevedra |
| Caixa Capital Risc | Balearic Islands |
| CaixaBank, S.A. | Valencia |
| CaixaBank, S.A. | |
| Caliboweb | Zaragoza |
| CalidadPrecio | Madrid |
| Call Centrix | Madrid |