| Anoop Systems | Barcelona |
| Answerbase | Barcelona |
| AntalGenics, S.L. | Alicante |
| Antares Servicios Informáticos | Madrid |
| Antaviana | Lleida |
| Antea Group | A Coruña |
| Antel Consultoría Informática y Telecomunicaciones, S.L. | Madrid |
| Antimalwares | Madrid |
| Antivirus Global Services, S.L. | Madrid |
| Antonio Peñalva | Alicante |
| Anunzia Solucions Tecnologiques, S.l. | Barcelona |
| Anvimur Telecomunicaciones, S.L. | Murcia |
| Anyverse, S.L. | Madrid |
| Apache Digital | Madrid |
| Apara | Madrid |
| APD Algoritmos Procesos y Diseños, S.A. | Madrid |
| APE Software Components, S.L. | Barcelona |
| Apen Centre Informàtic, S.L. | Barcelona |
| Aperton Electronics | Valencia |
| Apices | Madrid |
| Apiumhub | |
| APlanet | Biscay |
| Aplazame | Madrid |
| Aplicaciones Electrónicas Quasar, S.A. | Madrid |
| Aplicaciones en Informática Avanzada, S.L. | Barcelona |
| Aplicaciones.AI | |
| Aplitec Informàtica, S.L. | Girona |
| App Design | Madrid |
| App&Web | Granada |
| AppAquí | Barcelona |
| AppFutura | Barcelona |
| Appglobal | Madrid |
| AppGround | Santa Cruz de Tenerife |
| Apple La Maquinista | Barcelona |
| Apple Parquesur | Madrid |
| Apple Xanadú | Madrid |
| Applied Research using OMIC Sciences, S.L. | |
| Applivery, S.L. | Madrid |
| Appnormals Team, S.L. | Barcelona |
| apps4two | Valencia |
| Appylan Solutions | Madrid |
| ApSIC, S.L. | Barcelona |
| APSL Tech | Balearic Islands |
| AptaTargets, S.L. | Madrid |
| Aptus Biotech | Madrid |
| Aqua eSolutions | Madrid |
| Aquora Business Education, S.L. | |
| Araclon Biotech | Zaragoza |
| Araelec, S.L. | Zaragoza |
| Aragonese Foundation for Research & Development | |