| Sutor Bank GmbH | Hamburg |
| Sutter Verzeichnisverlag GmbH & Co. KG | |
| SVA GmbH | Hamburg |
| Sven Brandenburger | Baden-Württemberg |
| svs Capital Partners GmbH | |
| SWAP Computer GmbH | Baden-Württemberg |
| Swarm Logistics GmbH | |
| SWD GmbH | Schleswig-Holstein |
| Swenggco Software | |
| SWH Software GmbH | Berlin |
| Swift Weekly | North Rhine-Westphalia |
| swift.consult GmbH | North Rhine-Westphalia |
| SwiftMQ | Bremen |
| Swiss IT Security Group AG | Hesse |
| SWM Stadtwerke München GmbH | Bavaria |
| SWMS Systemtechnik Ingenieurgesellschaft mbH | Lower Saxony |
| SWN (Südwest Network) oHG | |
| Swobbee GmbH | |
| SWS Computersysteme AG | Bavaria |
| SwS Göttingen GmbH | Lower Saxony |
| Swyx Solutions AG | North Rhine-Westphalia |
| SYBCOM GmbH | Saarland |
| Sybera GmbH | Baden-Württemberg |
| Syborg | Saarland |
| Syborg Studios | |
| Sycat IMS GmbH | Lower Saxony |
| SYCON Beratungsgesellschaft mbH | North Rhine-Westphalia |
| Sycor GmbH | Lower Saxony |
| Sydatec | Berlin |
| Syka-Soft GmbH & Co. KG | Bavaria |
| Sylbek | Baden-Württemberg |
| Sylphen GmbH & Co. KG | Hesse |
| Sylsch GmbH | Saxony-Anhalt |
| Symanto | Bavaria |
| SYMAX Business Software AG | Hesse |
| Symbiosys2 | |
| SymbioWare IT GmbH | Bavaria |
| Symferon GmbH | Hesse |
| Symmedia GmbH | North Rhine-Westphalia |
| Symmetrix Design & Hosting | Hesse |
| sympacon Beratungsgesellschaft mbH | Lower Saxony |
| Sympatient GmbH | |
| SYMPLASSON Informationstechnik GmbH | Hamburg |
| Symweb GmbH | Baden-Württemberg |
| synalis GmbH & Co. KG | North Rhine-Westphalia |
| Synapse Audio Software | Baden-Württemberg |
| Synapsy Mobile Networks GmbH | Bavaria |
| Synaptic Network GmbH | Bavaria |
| Synaptic Systems GmbH | |
| Synapticon GmbH | |