| Neuromod Devices Ltd | |
| New Frontiers Enterprise Ireland | |
| New Horizons Ireland | Dublin City Council |
| New Ross Credit Union Ltd | |
| NewsWhip | Dublin City Council |
| Nexus Innovation Centre | Limerick City and County Council |
| Niceone Ltd | Dublin City Council |
| No1 SEO IRELAND | |
| Noden Pharma DAC | Dublin City Council |
| NoFrixion Ltd | |
| Noloco | |
| NomuPay | |
| Norio Ventures Ltd | |
| Northside Partnership Ltd | |
| Nostra Systems | South Dublin County Council |
| Novi Financial, Inc. | Dublin City Council |
| Novus Diagnostics Ltd | |
| NUACOM | |
| Nualtra | |
| Nuasoft Web Services | Dublin City Council |
| Numra | |
| Nuritas | Dublin City Council |
| Nutshell Creative Communication | Cork City Council |
| Nvolve | |
| Obit | Limerick City and County Council |
| Oblivious Software Ltd | |
| Ocuco Ltd | Fingal County Council |
| Office Suites | |
| Offr.io | |
| Olas.ie | Dún Laoghaire-Rathdown County Council |
| Onaware | Waterford City and County Council |
| OnePageCRM | Galway City Council |
| OnePosting | Dublin City Council |
| ONK Therapeutics Ltd | |
| Online365.ie | Dublin City Council |
| ONS Ltd | Clare County Council |
| OnSight Designs Ltd | Limerick City and County Council |
| OnTheWeb | Galway City Council |
| OPCWare | Cork City Council |
| Openet | Dublin City Council |
| OpenMind | Dublin City Council |
| OpenPoint | Limerick City and County Council |
| OpenSky | |
| OpinionX Ltd | |
| Oracle Ireland | Dublin City Council |
| Orbigo Solutions Ltd | Dublin City Council |
| Orbit Technologies Dublin | |
| Orbsen Therapeutics | |
| Origin Enterprises plc | |
| Origina | Dún Laoghaire-Rathdown County Council |