| Motor Valley Accelerator | Modena |
| MotorK | Milan |
| Mottura S.p.A. | Turin |
| MotusQuo S.r.l. | |
| MOVEANDCALL S.r.l. | Rome |
| Movendo Technology S.r.l. | |
| Moviement S.r.l. | Padua |
| Movinfo S.r.l. | Monza and Brianza |
| Moxoff S.p.A. | |
| Moze S.r.l. | Milan |
| MPE S.r.l. | Varese |
| MRS Solutions S.a.s. | Naples |
| MSB Software | Ravenna |
| MT Distribuzione S.r.l. | Verona |
| MTI | Milan |
| MTN Company S.r.l. | Salerno |
| Mugo S.r.l. | |
| Multi Advanced Project | Rome |
| MultiData S.r.l. | Modena |
| Multimedia S.r.l.s. | Bari |
| MultiMedia Soft | Turin |
| Multimedia Web Services | Cagliari |
| MultiMediaVda | Aosta Valley |
| MULTIWAYS//E-Strategies | Friuli-Venezia Giulia |
| MultiWire S.r.l. | Cuneo |
| Muscope Cybersecurity S.r.l. | |
| Mweb solution | Milan |
| My cool button | Padua |
| My Store | Rome |
| My-Money | Padua |
| myAEDES | Naples |
| myAVA | South Tyrol |
| MyNet S.r.l. | |
| MySoft Consulting S.r.l. | |
| MyTechnology | Lecco |
| N&TS GROUP Networks & Transactional Systems Group S.p.A. | Milan |
| N&W Global Vending S.p.A. | Bergamo |
| n-Track S.r.l. | |
| Nahweb | Cuneo |
| Namirial S.p.A. | Ancona |
| NanoPhoria S.r.l. | |
| NanoSiliCal Devices S.r.l. | |
| Nanosystems S.r.l. | |
| Natel | Milan |
| Nautilus Mediterranean eXchange | Rome |
| Naxa S.r.l. | Milan |
| NBS di Giovanni Bassetti | Bari |
| nCore S.r.l. | |
| ND Web Agency | Bologna |
| NDB Web Service S.r.l. | Naples |