| Dapp | |
| Databilio | Mexico City |
| Dataproducts de México S.A. de C.V. | Mexico City |
| DataShield | Mexico City |
| DB Menos | Mexico City |
| DB menos | |
| DEK Automation de Puertas | State of Mexico |
| Delta Networks Systems | Mexico City |
| Desarrollo de Sistemas Profesionales | Mexico City |
| Desarrollo de Sistemas Tiempo.Resultados | Quintana Roo |
| Desarrollo y Capacitación en Internet S. A. de C. V. | Mexico City |
| Desarrollos Electrónicos y Eléctricos, S.A. de C.V. | Mexico City |
| Design Works | Nuevo León |
| DEV.F | Mexico City |
| Development & Net Consulting, S.A. de C.V. | Mexico City |
| Diamond Networks S. de R.L. de C.V. | Nuevo León |
| Diesvi Desarrollo Informático, S.C. | Mexico City |
| DigitalServer | Mexico City |
| Digitel Telecomm | Mexico City |
| Digitt | Jalisco |
| Dila Capital, S.A. de C.V. | Mexico City |
| DIM-ID | Mexico City |
| Dinámica Heurística | Nuevo León |
| Dinetsys Conmutadores IP | Jalisco |
| Direnet | Nuevo León |
| Disegno.com.mx | Yucatán |
| DistritoWeb | Mexico City |
| Doopla | |
| dotNET Desarrollo de Sistemas | Quintana Roo |
| DSCORP | Mexico City |
| DTI | Mexico City |
| DyG Global | Mexico City |
| E birlain | Mexico City |
| E soft | Sinaloa |
| E Tech Consulting, S.A. de C.V. | Nuevo León |
| E&T Internet Consulting | Mexico City |
| E-multimedia | Guanajuato |
| e-personal | Jalisco |
| E-Software | Nuevo León |
| Ebatial, S.A. de C.V. | State of Mexico |
| eConDev Consulting & Development | Mexico City |
| Ecoprodel | Puebla |
| Ecosoft | Mexico City |
| Eden | Mexico City |
| Edgebound | Mexico City |
| Eduardo Vilso | Yucatán |
| Efecto Huella | Jalisco |
| Efektiva | |
| eFlow | Mexico City |
| Ekatar | Jalisco |