| Bibliosoft, Lda | Lisbon |
| BindTuning | |
| Bioglobal, S.A. | Lisbon |
| Biometrid | Porto |
| BioPremier | Lisbon |
| biosurfit, S.A. | Lezíria do Tejo |
| Bison Bank | Lisbon |
| Bitcliq | Região de Leiria |
| Bizno Solutions | Porto |
| Blip | Porto |
| Bliss Applications | Lisbon |
| Bloq.it | Lisbon |
| Blue Bio Value | Lisbon |
| Blueclinical Ltd | Porto |
| Blueshark Studio, Lda | Lisbon |
| Bluetech Accelerator | Lisbon |
| BMD Software | Região de Aveiro |
| Bondlayer | Porto |
| Braintrust, S.A. | Lisbon |
| Brandtellers Studio | Região de Aveiro |
| Breeze Media | Lisbon |
| Brighten Consulting, S.A. | Lisbon |
| Bug Group | Lisbon |
| Build Up Labs | Lisbon |
| Buildcode | |
| Builtrix | Lisbon |
| Buzzvel | |
| Byclosure, Lda | Lisbon |
| BYDAS, Digital Communication Agency, Lda | Porto |
| BYND | Lisbon |
| Bynet | Porto |
| BySide | Porto |
| BytePitch | Porto |
| C-mo Medical Solutions | Lisbon |
| C2C NewCap | Lisbon |
| Caixa Capital | Lisbon |
| Caixa Mágica Software | Lisbon |
| Capital Games | Lisbon |
| Carnegie Mellon University Portugal | Lisbon |
| Casafari Europe Ltd | Lisbon |
| Católica Lisbon School of Business & Economics | Lisbon |
| CEC | Lisbon |
| Cegid Vendus | |
| CellmAbs | Oeste |
| Centro de Computacao Grafica | Ave |
| Centro Internacional de Matemática | Lisbon |
| Centro Nacional de Cibersegurança Portugal | Lisbon |
| Champalimaud Foundation | |
| China Facture | Lisbon |
| chrome.pt | Lisbon |