| Poolbeg Pharma | |
| Popcorn Web Design Ltd | |
| Popi | Kent |
| Poplar Studio | |
| Popokatea | Devon |
| Poppy Design & Graphics Ltd | Moray Council |
| Poq | Greater London |
| Porotech | |
| Port-P Ltd | West Midlands |
| Portal Biotech Ltd | |
| Portal Technologies | |
| PortaPow Ltd | |
| Portech Systems Ltd | West Midlands |
| Portfolio Ventures Ltd | |
| Portsmouth Business Systems Ltd | Hampshire |
| Portsmouth Communications Ltd | Hampshire |
| PortSwigger | Cheshire |
| Porvair Sciences Ltd | |
| POS Ltd | West Yorkshire |
| Posilan Ltd | |
| Positech Games | |
| Position1SEO | |
| Positive Computing Ltd | Berkshire |
| Positive Internet Company | |
| Positive Internet Marketing Ltd | |
| Positive IT Communications | Carmarthenshire |
| Positive Logic | |
| Positive Solutions Ltd | |
| Positive Web Design | Cheshire |
| Positive Web Solutions | |
| Positively Online | South Yorkshire |
| Post Production Consultants Ltd | Buckinghamshire |
| Post Quantum | |
| Post Script Design | Bedfordshire |
| PostGraphile | |
| Postroom-Online.co.uk | Northamptonshire |
| Potato London Ltd | |
| Potential.co | |
| Potential.ly | |
| Potenza Technology Ltd | |
| Poundbury Systems Ltd | |
| Power Action Ltd | Lisburn and Castlereagh |
| Power Computing Ltd | Bedfordshire |
| Power Electrics Ltd | Staffordshire |
| Power Electronic Measurements Ltd | Nottinghamshire |
| Power Inspired Ltd | Oxfordshire |
| Power Roll Ltd | County Durham |
| Powercode Consulting Ltd | |
| PowerConnections | Essex |
| Powered By Coffee Ltd | |