| Tyntec | |
| Type Rite 08 Ltd | Newry, Mourne and Down |
| Tyresoft Ltd | |
| U Refill Toner Ltd | West Midlands |
| UAS Enterprises Ltd | Cornwall |
| Ubamarket Ltd | |
| Uber Digital Ltd | |
| Uberweb | Tyne and Wear |
| UBIO Ltd | Greater London |
| Ubiquigent Ltd | |
| Ubisecure, Inc. | |
| Ubisense | Cambridgeshire |
| Ubuntu | |
| UC4 | West Midlands |
| UCL Business Ltd | |
| UCL Partners | |
| UCL Quantum Science & Technology Institute | |
| UCS | West Midlands |
| uDream Solutions Ltd | Greater London |
| UENI Ltd | Greater London |
| UFO Design | East Sussex |
| Ufonia Ltd | |
| UFORIKA | |
| Uhura Solutions Ltd | Greater London |
| UK Access User Group | Gloucestershire |
| UK Biobank Ltd | Greater Manchester |
| UK Business Angels Association | |
| UK Business IT Ltd | |
| UK Circuits and Electronics Solutions Ltd | Greater Manchester |
| UK Collaborative Computational Projects | Cheshire |
| UK Data Archive | |
| UK Datahouse | |
| UK Design Group | Staffordshire |
| UK Dev Ltd | |
| UK Domains | Merseyside |
| UK Finance Ltd | |
| UK Free Software Network | Hertfordshire |
| UK Gaming Computers Ltd | Essex |
| UK Ink Supplies | Lincolnshire |
| UK Internet Sites Ltd | |
| UK IT Networks Ltd | Cheshire |
| UK IT Recycling Ltd | Shropshire |
| UK Language Solutions Ltd | |
| UK Logo Designs | |
| UK Marketing Management Ltd | |
| UK PropTech Association Ltd | |
| UK Research and Innovation | |
| UK Robotics | |
| UK Software Company Ltd | |
| UK Solar Generation | |