| Yorkshire Mac User Group | West Yorkshire |
| Yorkshire Payments | |
| Yorkswebsites.co.uk | |
| Yorktech Solutions | |
| Yorsipp Ltd | |
| Yosh.AI Ltd | Greater London |
| Yoshki | |
| Yospace Technologies Ltd | |
| YoTech | |
| Yoti | Greater London |
| Yotta | Warwickshire |
| Yotta Solutions Ltd | |
| You Capital | |
| YOU Systems | Cambridgeshire |
| Youmanage HR Ltd | Stirling |
| Young Enterprise Scotland | |
| Your Business Mobile | |
| Your Cloud Works Ltd | |
| Your Dev Team | Leicestershire |
| Your e Solutions Ltd | South Yorkshire |
| Your Geek Friend | Gloucestershire |
| Your Impact Ltd | Gloucestershire |
| Your IT Department Ltd | Nottinghamshire |
| Your Juno | |
| Your Office Anywhere | Lancashire |
| Your Online Mechanic | Greater Manchester |
| Your Site Here | Hampshire |
| Your Storage Box Ltd | |
| Your Web Designer | Derbyshire |
| your-own-page | Dorset |
| Yourgene Health | Greater Manchester |
| YourParkingSpace | Greater London |
| Yoyo Games | |
| Yozobi | Greater London |
| Yozu Ltd | |
| YP Solutions Ltd | Lancashire |
| yReceipts Ltd | Greater London |
| YU Life | Greater London |
| Yudu Ltd | Lancashire |
| Yunasko Ltd | |
| YunoJuno Ltd | |
| Yuuzuu Ltd | Greater Manchester |
| Yuva Consultants Ltd | Glasgow |
| YZ Designs Ltd | Bristol |
| Z Design UK Ltd | Buckinghamshire |
| Z Soft Solution Ltd | |
| Z-Host | Hampshire |
| Z100 Community Ltd | |
| Zafire Ltd | Oxfordshire |
| Zahara Systems Ltd | |