| Epsitec S.A. | Vaud |
| Epteca GmbH | |
| Epure S.A. | Fribourg |
| EquipE Solutions AG | Zurich |
| EraCal Therapeutics Ltd | |
| ErgoDent | Zurich |
| Ergon Informatik AG | Zurich |
| Ergonomics AG | Zurich |
| Ergosoft | Thurgau |
| ERNI Schweiz AG | Zurich |
| Ernst + Partner AG | Zurich |
| Ernst Basler + Partner AG | Zurich |
| Escapenet.ch GmbH | Zurich |
| ESGroup AG | Zurich |
| EsoCap AG | |
| ETH Zürich - Department of Computer Science | |
| ETH Zürich - Department of Information Technology and Electrical Engineering | Zurich |
| ETH Zürich - Distributed Computing | Zurich |
| ETH Zürich - Distributed Systems Group | Zurich |
| ETH Zürich - Institute of Computer Systems | Zurich |
| ETH Zürich - Institute of Robotics | Zurich |
| ETH Zürich - Institute of Theoretical Computer Science | Zurich |
| ETH-Rat | Zurich |
| Ethereum | Zug |
| Ethereum Research | |
| Etrion Corporation | Geneva |
| Eulitha AG | |
| Euraconsult GmbH | Basel-Stadt |
| Euresearch | Bern |
| Eurisco S.à.r.l. | Ticino |
| Eurographics | Geneva |
| EuroPython | Basel-Stadt |
| Eurospider Information Technology AG | Zurich |
| Evalueserve AG | Schaffhausen |
| Evatec AG | |
| Eventor | |
| EverdreamSoft S.A. | |
| Evnnovatis Schweiz AG | Solothurn |
| Evok | Fribourg |
| Evolute AG | |
| ExcellGene S.A. | |
| ExcellGene S.A. | |
| Execute GmbH | Zurich |
| Exeon Analytics AG | Zurich |
| EXES S.à.r.l. | Neuchâtel |
| Exnaton AG | |
| Exoscale | Vaud |
| Expersoft Systems AG | Zug |
| ExpertSoft GmbH | Zug |
| exQuisito | Bern |