| Levitronix GmbH | |
| Lifecom Neue Medien | Lucerne |
| Light Chain Bioscience | |
| Lightly AG | |
| LimmaTech Biologics AG | |
| Limula S.A. | |
| Linalis S.à.r.l. | Geneva |
| Lineasoft Sagl | Ticino |
| Linkster Therapeutics | Zurich |
| Linux User Group Bern | Bern |
| Linux User Group Switzerland | Zurich |
| Linuxfabrik GmbH | Zurich |
| Liquity AG | |
| Lisk | Zug |
| Litecom AG | Aargau |
| Littlebit Technology AG | Zug |
| LivingTech GmbH | Zurich |
| LocalBini AG | |
| Locatee AG | |
| Loft Dynamics AG | |
| Logex AG | Bern |
| Logic Informatique | Vaud |
| LogiServe S.A. | Basel-Stadt |
| Logitech | |
| Logitech Europe S.A. | Vaud |
| Logmind | |
| LogoCom D.Collet | Bern |
| LogWin S.à.r.l. | Fribourg |
| Lonza | |
| Loomes | Zurich |
| Loop Medical S.A. | |
| Looria | |
| LoThoSoft | Valais |
| Loway | Ticino |
| Luciol Instruments S.A. | Vaud |
| Luciole Medical AG | |
| Ludomedia | Vaud |
| Luganet S.A. | Ticino |
| Luginbuehl.com | Bern |
| LUI.IS, LLC | Ticino |
| Lumatron AG | Aargau |
| Lunaphore Technologies S.A. | |
| Lyfegen HealthTech AG | |
| Lykke, Inc. | Zug |
| LYO-X AG | |
| Mabylon AG | |
| machineMD AG | |
| Macrobi GmbH | Thurgau |
| Macrogram S.A. | Vaud |
| MacServices | Valais |