| Bersier Information Technologies | Fribourg |
| bestview GmbH | Zurich |
| BETA CAE Systems International AG | Lucerne |
| Betatronics Services AG | Zurich |
| Bexio AG | |
| Bezirks-Sparkasse Dielsdorf | |
| BGO Software | |
| BigHosting | Zurich |
| Billte AG | |
| BinaryEdge AG | Zurich |
| BinaryEdge AG | |
| Binatec Ingenieure AG | Uri |
| BioCopy AG | |
| Biognosys AG | |
| BioID | Obwalden |
| BioLingus AG | |
| BioLingus AG | |
| Bionomous S.A. | |
| Bionter AG | |
| BioVersys AG | |
| BioXpress Therapeutics S.A. | |
| Biped.ai | |
| Bireva Software | Zurich |
| Bison Schweiz AG | Lucerne |
| Bistalk Telecom AG | Zug |
| Bitcoin Suisse AG | |
| Bitfold AG | |
| Biwac Webagentur | Solothurn |
| BizNet AG | Bern |
| BKS Kabel-Service AG | Solothurn |
| Black Box Network Services AG | Schwyz |
| Blackshield Capital Group | |
| Blanke | Aargau |
| Blattform | Basel-Landschaft |
| Blättler Kassensysteme GmbH | Schwyz |
| BLC Consulting AG | Zurich |
| Block Green | |
| Blockchain Source GmbH | Zug |
| Blocksport AG | |
| Blockstrom AG | |
| Bloom Biorenewables | |
| Bloom Diagnostics | |
| Bloomio AG | |
| Blue Butterfly | |
| Blue Call GmbH | Aargau |
| Blue Earth Capital AG | |
| Blue Horizon Corporation AG | |
| Blue Office Consulting AG | Lucerne |
| BlueGlass International Ltd | Zurich |
| Bluelion | |