| LSEC - Leaders In Security | |
| LSP.expert | |
| Ludus | |
| LuGus Studios | |
| Lusis Communication Responsable | |
| Luzmo | |
| LynxCare Clinical Informatics N.V. | |
| M-sphere | Flemish Brabant |
| MAC Telecom | Brussels-Capital |
| Madewithlove | Flemish Brabant |
| MaggiC Solutions | Liège |
| Mail.be | Brussels-Capital |
| Mainteneo | |
| MAMS Computers | Hainaut |
| Manol Networks | Limburg |
| Manual.to | |
| MAPA B.V.B.A. | West Flanders |
| Marbles | Antwerp |
| Marple | |
| Massive Media | East Flanders |
| Master Chips | East Flanders |
| Material S.A. | Brussels-Capital |
| Materialise N.V. | |
| Mathie Consulting | Liège |
| Mattias Geniar | |
| MCH Services | Brussels-Capital |
| MCProlog | Walloon Brabant |
| MDSoft S.P.R.L. | Namur |
| MeaWeb | Hainaut |
| MECOMS | |
| MedCalc | East Flanders |
| Media*A S.P.R.L. | Brussels-Capital |
| Media-Effect | East Flanders |
| Medialux | Luxembourg |
| Mediasoft B.V.B.A. | Limburg |
| MeDirect | |
| Medispring S.C.R.L. | |
| MedTech Flanders | |
| Mega-Tech Informatique S.P.R.L. | |
| Megabyte | Walloon Brabant |
| Megabyte | |
| Melexis | West Flanders |
| Meltem | Flemish Brabant |
| Mendoweb | Brussels-Capital |
| METALogic | Flemish Brabant |
| Metanous | |
| Metastore | Antwerp |
| MHConsultants S.R.L. | Hainaut |
| Microbus A.S.B.L. | Liège |
| Microsoft Belgium | Flemish Brabant |