| Sociedad de Matemática de Chile | Santiago Metropolitan |
| Softart S.p.A. | Santiago Metropolitan |
| SoftCapture Technologies | Santiago Metropolitan |
| Softgroup | |
| Softland | Santiago Metropolitan |
| SoftMedia | Santiago Metropolitan |
| Sofytec S.A. | Santiago Metropolitan |
| Soho Chile | Santiago Metropolitan |
| Soho Humantech | |
| Solnet SpA | Santiago Metropolitan |
| Solo Hosting | Santiago Metropolitan |
| Soluciones Tecnologicas Plataforma Ltda | Santiago Metropolitan |
| SolucionHost SpA | Santiago Metropolitan |
| Solutions | Santiago Metropolitan |
| Solutions for Everyone | |
| Soporta | |
| Sovos Compliance, LLC | Santiago Metropolitan |
| SoyFocus | Santiago Metropolitan |
| Start-Up Chile | Santiago Metropolitan |
| Startups Latam | Santiago Metropolitan |
| STCon S.p.A. | |
| StrixSoft | |
| Studio Pangea, Ltda | Santiago Metropolitan |
| Subsecretaría de Telecomunicaciones | Santiago Metropolitan |
| Sudo | |
| Super Hosting Chile | Santiago Metropolitan |
| Supplyline | Santiago Metropolitan |
| SW Software | Santiago Metropolitan |
| Symbiose S.p.A. | |
| Synaptic | Santiago Metropolitan |
| Tactech | |
| Talana | |
| Talento al Aula | |
| Tasman Web Developers | Valparaíso |
| Tchile WebHosting | Santiago Metropolitan |
| TCIT Cloud Solutions | Santiago Metropolitan |
| TECHNOlogies & Solutions, Ltda | Santiago Metropolitan |
| Tecno Agencia | Santiago Metropolitan |
| Tecnova | Santiago Metropolitan |
| Tedacom Ltda | Santiago Metropolitan |
| Teknos | Santiago Metropolitan |
| Telefonica Chile S..A | Santiago Metropolitan |
| Telefónica del Sur | Santiago Metropolitan |
| Teparatres | |
| Teraclic | Santiago Metropolitan |
| TestGroup Ltda | Santiago Metropolitan |
| TGI Mobile Systems | Santiago Metropolitan |
| The Ganesha Lab | Santiago Metropolitan |
| Thomas Signe | |
| TI Chile | Santiago Metropolitan |