| SMS Sudamérica | |
| Snappler | Buenos Aires |
| Snoop Consulting | Buenos Aires |
| SocialTools.me | Buenos Aires |
| Sociedad Argentina de Informacion | Buenos Aires |
| Sociedad Argentina de Informática | Buenos Aires |
| Sociedad Científica Argentina | Buenos Aires |
| Sofiana | Buenos Aires |
| Sofrecom Argentina | Buenos Aires |
| Softcom | |
| Softland Argentina | Buenos Aires |
| Software América | Buenos Aires |
| Software del Centro | Buenos Aires |
| Software Legal | Buenos Aires |
| SolSoft S.R.L. | Buenos Aires |
| Solsoftware | Buenos Aires |
| Soluciones Nexo, S.A. | Córdoba |
| Solutica Software Development Company | Buenos Aires |
| Sonda | Buenos Aires |
| Sooft Technology | Córdoba |
| Soporte Informático ViaNet | Buenos Aires |
| SpeechCompany | |
| Spinsoft | Buenos Aires |
| SQLMax Connections | Buenos Aires |
| Staff Codes | Buenos Aires |
| Start-Ups Argentina | Buenos Aires |
| Startup Buenos Aires | Buenos Aires |
| Storey S.A. | Buenos Aires |
| Stormtech Solutions | |
| Structured Intelligence | Buenos Aires |
| Studio Raica Design | Buenos Aires |
| Stylus | Buenos Aires |
| Stym Computación | Buenos Aires |
| Su Web Express | Buenos Aires |
| Subituweb.com | Buenos Aires |
| Sueños Digitales Argentina | |
| Summa Solutions | Buenos Aires |
| Super Desino Web | Buenos Aires |
| Supersistemas | Buenos Aires |
| Support Informática | Santa Fe |
| SUR Emprendimientos Tecnológicos, S.R.L. | Buenos Aires |
| SurEstudio | Buenos Aires |
| Surhive Design | Santa Fe |
| SURI | Buenos Aires |
| Surinter | Mendoza |
| Suris Code | |
| SYC Consulting, S.A. | Buenos Aires |
| Synagro | Buenos Aires |
| Syncromind | |
| Syntagma | Buenos Aires |