| Rongo University | |
| Rova Digital | Nairobi |
| Royal Web Experts | Nairobi |
| Ryanada | Nairobi |
| Safaricom | Nairobi |
| Sagana Technical Training Institute | |
| Said Company | |
| SasaHivi Media | Nairobi |
| SawaSawa.com Ltd | Nairobi |
| Scale Management Ltd | |
| Scott Christian University | |
| Secunets Technologies Ltd | Nairobi |
| Seen Technologies | |
| Sentinel Systems Ltd | Nairobi |
| Sevenseas Technologies | Nairobi |
| Shantec Systems Ltd | Nairobi |
| Shop I.T. | Nairobi |
| Sight & Sound Ltd | Nairobi |
| Silensec | Nairobi |
| Silqu | Nairobi |
| Simba Hosting | Nairobi |
| SimbaTrac | Nairobi |
| Simplify IT | Nairobi |
| Sino Soft Ltd | |
| Smart Applications International Ltd | |
| Smart Web Kenya | |
| Smartcode Technologies Ltd | |
| Smile Telecom Solutions Ltd | Nairobi |
| Sobbayi Network | Nairobi |
| SoftIQ Technologies Ltd | |
| Softlink Chain Ltd | Nairobi |
| Softlink Options | Nairobi |
| Softlink Options Ltd | Nairobi |
| SoftMas Solutions KE | Nairobi |
| Software Technologies Ltd | Nairobi |
| Sokowatch, Inc. | Nairobi |
| Solar Panda | |
| Solution Bridge International | Nairobi |
| South Eastern Kenya University | |
| Specicom Technologies Ltd | Nairobi |
| Speedex Marketing Services | |
| Spotted Anywhere Ltd | Nairobi |
| Sprout Media | Nairobi |
| St. Paul's University | |
| Star College of Management Studies | |
| StartUpAfrica | Nairobi |
| Stationcom | Nairobi |
| Strathmore University | Nairobi |
| Studialabs | |
| StudioSaba CreACTIVE | Nairobi |