| Ventureburn | Western Cape |
| Venue Muskett Design Studio | Gauteng |
| Veritas University Abuja | |
| Versys Media | Gauteng |
| Verticle Software | Western Cape |
| Viacad Design | Western Cape |
| Viadata | Western Cape |
| Viko Designs | Western Cape |
| VillageTelco | Western Cape |
| Vircap Services | Gauteng |
| Virtcom | KwaZulu-Natal |
| Virtual Internet Exchange | Western Cape |
| Virtual Mutsami | Western Cape |
| Virtual Tours | Western Cape |
| Virtually There | KwaZulu-Natal |
| Visability | Eastern Cape |
| Vision Network Solutions | Gauteng |
| Visions Consulting | Gauteng |
| Visuals Interactive | Western Cape |
| VitalClick | Gauteng |
| Vivant Design Studio | Gauteng |
| Vizi Solutions | Gauteng |
| Vizionxr Ltd | |
| Vodacom (Pty) Ltd | Free State |
| Voice Logger SA | Gauteng |
| Voice Recognition Systems | Gauteng |
| Voicelogic | Eastern Cape |
| Volt Development | KwaZulu-Natal |
| Vox Telecom | KwaZulu-Natal |
| VPOPS (Pty) Ltd | KwaZulu-Natal |
| VPS Servers | Western Cape |
| VTA Digital Solutions | Western Cape |
| VTS Communications | Western Cape |
| Vula Mobile | Western Cape |
| Vuselela TVET College | |
| W. H. Circuit CC | Western Cape |
| Walletdoc | Gauteng |
| Walsoft Computers | Gauteng |
| Walter Sisulu University | |
| Wanatel | Western Cape |
| Wanos Networks Pty Ltd | Western Cape |
| WAOHost.com | Gauteng |
| Warp Development | Gauteng |
| Water Research Commission | |
| Watobe Ltd | |
| Waxed Media | Gauteng |
| WDS Creative | |
| Web & IT Solutions International CC | Gauteng |
| Web AddiCT | Western Cape |
| Web Artist | Gauteng |