| Xploited Media | Western Cape |
| Xstream Flow (Pty) Ltd | Gauteng |
| Xtensive ICT Academy | Gauteng |
| Xtranet Internet Services | KwaZulu-Natal |
| Y2K Online Technologies | Gauteng |
| Yasha Software Consulting | Gauteng |
| YCIK Development | Western Cape |
| Yellow Lizard | Eastern Cape |
| Yesweb CC | Gauteng |
| Yoco Technologies | Western Cape |
| Yougottohaveit Web Designers | Gauteng |
| YourOnline | Western Cape |
| Yoyo Wallet | Western Cape |
| ZA Freelancer | Gauteng |
| ZA Web Hosting | Eastern Cape |
| Zabra.co.za | Gauteng |
| Zaio Technology | |
| ZAWebs | Eastern Cape |
| Zen Dynamics | KwaZulu-Natal |
| Zenertech | Western Cape |
| ZenZero | Western Cape |
| Zerksus Engineering | Gauteng |
| Zero Gravity Design | Western Cape |
| Zero-One-X Computer Services and Design CC | Gauteng |
| Zeus Communication, Multimedia & Development | Western Cape |
| Zircon Digital | Western Cape |
| Zomerlust System Design | Western Cape |
| ZonkeTech (Pty) Ltd | KwaZulu-Natal |
| Zootzone.com | Western Cape |
| Zulucom | KwaZulu-Natal |
| Zutari | Gauteng |