| 1Mentor | |
| 1on1 Consulting | |
| 1QB Information Technologies, Inc. | British Columbia |
| 1st Class Software | Ontario |
| 1st Data Recovery | British Columbia |
| 1st on the List Promotion, Inc. | British Columbia |
| 1StopPopup's Popup Creator | Quebec |
| 1UP Digital Marketing, Inc. | British Columbia |
| 1VALET | Quebec |
| 1WayFx Ltd | British Columbia |
| 1zero1 | |
| 2 Associés | Quebec |
| 2 Degrés | |
| 20-20 Technologies, Inc. | Quebec |
| 2000's Technology (3T), Inc. | Ontario |
| 2001 Audio Video | Ontario |
| 2020 DSS, Inc. | Alberta |
| 207 Media | Ontario |
| 20MegsFree.com | British Columbia |
| 23e2 Digital Marketing | Ontario |
| 24-7 Webs, Inc. | Ontario |
| 24/7 Systems and Networks, Inc. | Ontario |
| 247 Labs | Ontario |
| 247 Networks Ltd | British Columbia |
| 247-Host.ca | Quebec |
| 247hosts.com | British Columbia |
| 247NetSystems | Saskatchewan |
| 24x7 Web Hosting | Ontario |
| 2600 Montréal | Quebec |
| 295.ca | Ontario |
| 2bits.com, Inc. | Ontario |
| 2bone | British Columbia |
| 2csite.Net | British Columbia |
| 2DW | Ontario |
| 2G Solutions | Quebec |
| 2gen.net | Ontario |
| 2Keys | Ontario |
| 2kPlus Information Systems Consulting, Inc. | Ontario |
| 2KRS Computer Solutions | Ontario |
| 2Marketing Web Design & SEO Toronto | |
| 2Mtel Communications | Ontario |
| 2nd Age Systems, Inc. | Ontario |
| 2nd Floor Computers, Inc. | Alberta |
| 2nd Millennium Printers & Computers | British Columbia |
| 2P Tech | Ontario |
| 2Paths | British Columbia |
| 2S Water | |
| 2SEO.com | Ontario |
| 2Ship Solutions, Inc. | Ontario |
| 2web.ca | Saskatchewan |