| Name | Region |
|---|---|
| Zucara Therapeutics | |
| Zūm Rails, Inc. | |
| ZUUL, Inc. | Ontario |
| Zuum Global Services, Inc. | |
| Zwebra Web Studio, Inc. | |
| Zycomtec | Ontario |
| Zycoon Media | |
| Zygoat Creative Technical Services | British Columbia |
| Zymeworks, Inc. | British Columbia |
| Zync Communications, Inc. | Ontario |
| Zynik Capital | British Columbia |
| Zyra Media, Inc. | Ontario |
| ZyTech Software Solutions | Ontario |
| ZyTrax, Inc. | Quebec |
| ZYUS Life Sciences Corporation | |
| Zzeem | Ontario |
| [P1] Games |