| ZeMaas | Ontario |
| ZeMind Studios | Ontario |
| Zen Branding, Design & Com | Quebec |
| Zen Ebikes | |
| Zen Exits | |
| Zen Launchpad Network, Inc. | British Columbia |
| ZenduIT | |
| ZenFocus | Ontario |
| ZenFri, Inc. | |
| ZenHub | British Columbia |
| Zenisca | Ontario |
| Zenith Digital SEO | |
| Zenith Epigenetics Ltd | Alberta |
| ZenithMedia Canada | Quebec |
| Zenkis.ca | Quebec |
| Zensol | Quebec |
| Zensurance Brokers, Inc. | Ontario |
| Zenutech, Inc. | New Brunswick |
| Zenvision, Inc. | British Columbia |
| Zephyr IT Solutions | |
| Zephyr Ventures | Alberta |
| Zephyrus Innovations, Inc. | |
| Zéro huit | |
| Zero In | Ontario |
| Zero to Mastery, Inc. | Ontario |
| Zéro Un Zéro, Inc. | |
| Zero Worx, Inc. | Newfoundland and Labrador |
| ZeroBug Software | |
| Zerofractal Studio | Ontario |
| Zerohero Tech | |
| Zerokey | Alberta |
| Zerosum | Quebec |
| Zerotozenith Media | |
| Zeryx Software, Inc. | Quebec |
| Zesle Software, Inc. | |
| Zetane Systems | |
| Zeus Systems, Inc. | Ontario |
| Zeuter Development Corporation | Ontario |
| Zevahit | Ontario |
| Zevriv Solutions | Ontario |
| Zfactor | Ontario |
| ZGM Modern Marketing Partners | Alberta |
| ZiD Internet | Quebec |
| ZIDÉES | |
| Zighra | Ontario |
| Zigma8 | |
| Zilex Electronics, Inc. | Quebec |
| Zilia, Inc. | Quebec |
| Zillion Tech Consulting Services | |
| Zim Corporation | |