| Zination | |
| Zinger Web Design | Ontario |
| Zinreet Software Solutions | |
| Zion Industries, Inc. | Alberta |
| Zip TeleCom | Ontario |
| zipBoard Tech | |
| ZipLeaf Canada | Ontario |
| Zipnet Design | Alberta |
| ZippedScript Ltd | |
| Zircon Web Design, Inc. | Newfoundland and Labrador |
| Zire Media | Ontario |
| Ziva Dynamics, Inc. | British Columbia |
| ZL Social | Alberta |
| ZLC Financial | |
| Zmley, Inc. | |
| ZMO.AI | |
| Zoksh Pay | Ontario |
| Zolux Solutions | |
| Zonart Communication | Quebec |
| Zondicons | Ontario |
| Zone Accro.com | Quebec |
| Zone Atout | |
| Zone boréale Saguenay-Lac-Saint-Jean | Quebec |
| Zone d'innovation Sherbrooke Quantique | Quebec |
| Zone Infotech | |
| Zone One Digital | |
| Zone Startups | Ontario |
| Zone W3 Média Design, Inc. | |
| Zone1 Intellect, Inc. | Ontario |
| Zonetail, Inc. | Ontario |
| ZONETI | Quebec |
| ZongoTech | Quebec |
| Zoom Creation | Quebec |
| Zoom Media Group | Ontario |
| Zoom Software Solutions, Inc. | |
| ZoomCreative.com | Quebec |
| ZOOMi Technologies | |
| ZoomMed, Inc. | Quebec |
| ZoomTee | British Columbia |
| Zoop Mobility Network, Inc. | Quebec |
| ZopMedia | Ontario |
| Zorglobe | Quebec |
| Zoup Creative | Ontario |
| zPoint Products Company, Inc. | British Columbia |
| Zrafted | |
| ZTEST Electronics, Inc. | Ontario |
| ZTR | Ontario |
| Zú | Quebec |
| zu.com communications | Saskatchewan |
| Zubo Marketing | |