| Z-Man Games, Inc. | Quebec |
| Z3 Controls | Ontario |
| ZAA.CC | Quebec |
| Zaccak Solutions | Ontario |
| Zacxon, Inc. | |
| Zafin | Ontario |
| Zag | |
| Zahab Design | Ontario |
| Zaibz IT Services | |
| Zambah | Ontario |
| Zammit Consulting | Ontario |
| Zang-O-Fonts | Ontario |
| Zanotis, Inc. | Ontario |
| Zantek Information Technology, Inc. | Manitoba |
| Zanthic Technologies, Inc. | Alberta |
| ZAP | Quebec |
| Zap Creative | Saskatchewan |
| Zap Dramatic, Inc. | Ontario |
| ZAP Québec | Quebec |
| ZAP Sherbrooke | Quebec |
| ZappTek | Manitoba |
| Zartek Technologies Canada, Inc. | Ontario |
| Zaui Software | British Columbia |
| ZCOM System Group, Inc. | Ontario |
| ZCOM Systems Group, Inc. | Ontario |
| Zdelete | Ontario |
| ZE PowerGroup, Inc. | British Columbia |
| Zeal Media, Inc. | |
| Zebra Projects, Inc. | Alberta |
| Zecotek Photonics, Inc. | British Columbia |
| Zed Cellular | Quebec |
| Zed Graphic Communications, Inc. | Quebec |
| Zed Network, Inc. | |
| Zedi. Inc. | Alberta |
| zeeHIVE | |
| Zeffy | Quebec |
| Zeitspace, Inc. | Ontario |
| Zelexio | Quebec |
| Zeligsoft | Quebec |
| Zelmore Group | Alberta |
| Zelros | Quebec |
| ZeMaas | Ontario |
| ZeMind Studios | Ontario |
| Zen Branding, Design & Com | Quebec |
| Zen Ebikes | |
| Zen Launchpad Network, Inc. | British Columbia |
| ZenFocus | Ontario |
| ZenFri, Inc. | |
| ZenFri, Inc. | |
| ZenHub | British Columbia |