| Bluink Ltd | |
| BluRoot | |
| Bluum Technology | Ontario |
| BluWave, Inc. | Ontario |
| Blyth Academy | |
| BMAK Business and Technology Consultants, Inc. | Ontario |
| BMB Consulting Services, Inc. | Ontario |
| BMC Networks | |
| BMPS Software | British Columbia |
| BMU Augmented Intelligence | |
| BMV Optical Technologies, Inc. | Ontario |
| BNF Software | Quebec |
| BNH Expert Software | Quebec |
| BNP Paribas au Canada | |
| Boardstat | |
| Boast | |
| Bob Gillespie | |
| Bochsler Creative Solutions | Ontario |
| Bock Optronics, Inc. | Ontario |
| Bodycote | |
| Boehringer Ingelheim (Canada) Ltd | Ontario |
| Bogus Communication | Quebec |
| BOLD | Ontario |
| Bold Commerce | Manitoba |
| Bold Media Group, Inc. | British Columbia |
| Bold Therapeutics, Inc. | |
| Bollé Communications | Quebec |
| Bolster | |
| Bolt Media, Inc. | Ontario |
| Bolt Mobile | Saskatchewan |
| BoltonSmith | Ontario |
| Bombardier | |
| Bombes Créatives | Quebec |
| Bonavista Computer Systems | Alberta |
| Bond Capital | |
| Bonded Design | Alberta |
| BondNet | Ontario |
| BONE creative | British Columbia |
| Bonfire Development, Inc. | |
| Bonfire Interactive | Ontario |
| Bonjour Startup Montréal | Quebec |
| Book4time | |
| BookingAutomation.com | |
| BookitLab | |
| Bookmark Your Life, Inc. | Ontario |
| BookSteam | Ontario |
| Boom Digital Media Group | Ontario |
| Boom I.T. Group | Newfoundland and Labrador |
| Boom12 | Nova Scotia |
| Boomers Computers | British Columbia |