| EXirius IT Dienstleistungen GmbH | Saarland |
| exITed | Hesse |
| exito GmbH & Co. KG | Bavaria |
| EXO IT Solutions GmbH | |
| Exolaunch GmbH | |
| ExoMatter GmbH | |
| Exorbyte GmbH | Baden-Württemberg |
| expeer GmbH | North Rhine-Westphalia |
| Experience One | Baden-Württemberg |
| Experience Pc GmbH | Lower Saxony |
| Experimenta gGmbH | |
| Expert Minds GmbH | |
| Expertcloud.de GmbH | |
| ExperTeach Gesellschaft für Netzwerkkompetenz mbH | Hesse |
| Experteam GmbH | |
| Experteer GmbH | |
| Expertiger | |
| Expertlead GmbH | |
| expertum Holding GmbH | |
| Explainr | |
| Explicat Pharma GmbH | |
| Exploring JS: JavaScript books for programmers | |
| Explosion | Berlin |
| expopartner GmbH | |
| Exporo AG | Hamburg |
| exposed GmbH | Hesse |
| Express Ventures Beteiligungs GmbH | |
| ExpressGroup GmbH | |
| exsys Internet+Software UG (haftungsbeschränkt) | Lower Saxony |
| EXSYS Vertriebs GmbH | |
| EXT Excellent Training e.K. | |
| Extangis Business & Products GmbH | Saarland |
| Extantia Capital Management GmbH | |
| EXTOLL GmbH | |
| EXTRA Computer GmbH | Hesse |
| Extra-net24 AG | |
| eXtrabyte | Hesse |
| extragroup GmbH | North Rhine-Westphalia |
| Extrememarkup | Bavaria |
| eXtro media GbR | |
| EXWE GmbH | |
| Exxeta AG | |
| Exyte GmbH | |
| EY Startup | |
| eye2m GmbH | Lower Saxony |
| EyeEm Mobile GmbH | |
| eyefactive GmbH | |
| Eyeled GmbH | Saarland |
| eyelikeit | North Rhine-Westphalia |
| Eyeo GmbH | North Rhine-Westphalia |