| Especial Digital GmbH | |
| Espectum GmbH | Bavaria |
| Esphere Network | |
| Espiridon GmbH | |
| ESplan GmbH | North Rhine-Westphalia |
| EsPresto AG | Berlin |
| EsprIT Systems | Baden-Württemberg |
| ESR Pollmeier GmbH | Hesse |
| ESRI Deutschland GmbH | Bavaria |
| ESS GmbH | Baden-Württemberg |
| EST Engineering Systems Technologies GmbH & Co. KG | Rhineland-Palatinate |
| estag Capital AG | Berlin |
| Estec Energiespartechnik GmbH | Bavaria |
| eStrategy Consulting GmbH | |
| esw GmbH & Co. KG | North Rhine-Westphalia |
| ESW Software Warda GmbH & Co. KG | |
| ESYS GmbH | Berlin |
| eszett kreativagentur | Bremen |
| ET System Electronic GmbH | Baden-Württemberg |
| et-systems GmbH | |
| Etalytics GmbH | |
| ETAS GmbH | Baden-Württemberg |
| ETB Electronic Team Beratungs- und Vertriebs GmbH | Lower Saxony |
| etc. software GmbH | |
| Eteleon GmbH | Hesse |
| Eternygen GmbH | |
| ETH-Messtechnik GmbH | Baden-Württemberg |
| ETHR Digital Matter GmbH | |
| Ethris GmbH | |
| ETI GmbH | Baden-Württemberg |
| etis GmbH | Rhineland-Palatinate |
| etiscan Identifikationssysteme GmbH | Hesse |
| ETK networks solution GmbH | Bavaria |
| etone intermedia GmbH & Co. KG | Bavaria |
| ETOS GmbH | North Rhine-Westphalia |
| ETU Software GmbH | North Rhine-Westphalia |
| Etvas GmbH | |
| etventure GmbH | Berlin |
| ETW GmbH | |
| EU Business School Munich GmbH | |
| EU Werbeagentur GmbH | North Rhine-Westphalia |
| EU-Startups | Bavaria |
| euhost.com | Bavaria |
| EULANDA Software GmbH | Hesse |
| Eumara European Marketing Alliance AG | Saarland |
| EUMETSAT | Hesse |
| EUMLab Xanin Technology GmbH | |
| Eunetic GmbH | |
| euNetworks | Hesse |
| euNetworks GmbH | Hesse |