| Name | Region |
|---|---|
| Supercreative | |
| Superdev | |
| SuperGlobules | Métropole de Lyon |
| Supermood | |
| Superpictor | |
| Superpitch | |
| Superprof | |
| Supersonic Imagine | |
| Supersonic Imagine | |
| Supersoniks | Indre-et-Loire |
| Superspace | |
| SUPINFO | Paris |
| Supralog | Alpes-Maritimes |
| Sur Place - À Emporter | |
| SûretéGlobale.Org | |
| Surfe | |
| Surfy S.A.S. | |
| SurgiMab | |
| Survision | Hauts-de-Seine |
| Sutunam France | Métropole de Lyon |
| SVEG Télécom | Morbihan |
| SVGminify.com | |
| Swapcard | |
| Sweb Développement | Charente-Maritime |
| Sweego | |
| Sweep | Hérault |
| Sweetch Energy | |
| Swile | |
| Switch-Ti S.A.R.L. | Isère |
| SXD-Groupe | |
| Sycorax | |
| SYD Digital Care | Loire-Atlantique |
| Sydev | Isère |
| Sylfen | |
| SYLOB S.A.S. | Tarn |
| Syloe | Hérault |
| Sylq | |
| Symbiose Informatique | Paris |
| Symes | Alpes-Maritimes |
| Symfony | Hauts-de-Seine |
| Symotronic SE | Métropole de Lyon |
| Synactis | Yvelines |
| Synaps Informatique | Savoie |
| Synapse Biomedical, Inc. | |
| Synapse Informatique | Hérault |
| Synapse Medicine | |
| Synapses | Paris |
| Synchronext | |
| Synchronized | |
| Synchroteam | Hauts-de-Seine |