| TuxFamily | Paris |
| TVH Consulting | Yvelines |
| TVM Technologie | Hauts-de-Seine |
| TVPaint | Moselle |
| TwicPics S.A.S. | |
| Twinin | |
| TWINPIX | |
| TwinswHeel | |
| TXCube | |
| TYLIA Invest S.A.S. | |
| Tyms S.A.S. | |
| Typofonderie | Hauts-de-Seine |
| Tysep | Haute-Savoie |
| UAVIA | |
| Ubble | Paris |
| Ubiq | |
| Ubiquid | |
| Ubisoft | Seine-Saint-Denis |
| Ubiwan | Gironde |
| Ubuntu-fr | Paris |
| Ucanss | |
| Ucatchit | Paris |
| UCC-Experts | |
| Ugocom | Vaucluse |
| UGP International | Seine-Saint-Denis |
| UIT Nice Côte d'Azur | Alpes-Maritimes |
| Ulteam Informatique | Métropole de Lyon |
| Ultra Petita | |
| Ultranoir | Paris |
| Ulys Soft | Haute-Savoie |
| Ulysse | |
| Umanéa | |
| Umanis | Hauts-de-Seine |
| Umaps | |
| Umazuma | Paris |
| UMI | Métropole de Lyon |
| Unami | |
| Unblog.fr | Paris |
| UnderNews | Val-d'Oise |
| Unicancer | |
| UNICEM | |
| UNID | Nord |
| Unikbase | |
| Unikweb S.A.R.L. | Paris |
| UniLaSalle | |
| Unilease S.A. | Hauts-de-Seine |
| Unilink | Hauts-de-Seine |
| UniMédia | Maine-et-Loire |
| Union des Banques Arabes et Françaises | |
| Unistellar | |