| EMBA Business School | |
| Emeka | |
| Emencia | Paris |
| Emerging Valley | Bouches-du-Rhône |
| Emersya | |
| Emil | |
| Emissive | |
| EMIT | Moselle |
| Emjysoft | Drôme |
| Emka Électronique | |
| Emma | Vaucluse |
| Emmanuel GIBOUR | Indre-et-Loire |
| Emosis Diagnostics | |
| EMOTIC | |
| Emoxa | |
| Empirik | |
| Empreinte | Paris |
| Empreinte Digitale | Maine-et-Loire |
| Emulseo | |
| En Carta Diagnostics | |
| ENACO | |
| Enchanted Tools | |
| Enciris Technologies S.A.S. | Tarn |
| Encre Sepia | Pyrénées-Atlantiques |
| Encre.com | Val-de-Marne |
| Endodiag | |
| Endrix | |
| ENE | Métropole de Lyon |
| Enedis | |
| ENENSYS Technologies | Ille-et-Vilaine |
| Enerbee Technology | |
| Enerdigit | |
| Enerfip | |
| Energic | |
| Enero | Paris |
| ENERPLAN | Bouches-du-Rhône |
| ENEWS | Paris |
| Enez Solutions | |
| Engenius-Distribution S.A.S. | Paris |
| Engie | |
| ENI École Informatique | Loire-Atlantique |
| ENI Service | Loire-Atlantique |
| eNiX | Paris |
| Enjin S.A.R.L. | Maine-et-Loire |
| Enko | Ille-et-Vilaine |
| Ennov | |
| Enovacom | Bouches-du-Rhône |
| Enovos | |
| ENS de Lyon - Laboratoire de l'Informatique du Parallélisme | Métropole de Lyon |
| ENS Rennes | |