| Students.pl Sp. z o.o. | |
| Studio Albert Design | Masovian |
| Studio APLET | Masovian |
| Studio Coworking | |
| Studio Graficzne | Masovian |
| Studio Kreacji | |
| Studio Leopard | |
| Studio Wektor Sp. j. | |
| Studio Whizz | Silesian |
| Studio72 | Silesian |
| Studioars | Lesser Poland |
| Studioh | Pomeranian |
| StudioStrona | Subcarpathian |
| STX Next | |
| Success Craft | |
| Sugester | Masovian |
| Summ-IT | |
| Sun Capital Sp. z o.o. | Lower Silesian |
| Sun Group | |
| Suncode Sp. z o.o. | |
| Sunnet.pl | Pomeranian |
| Sunrise System | |
| Sunscrapers Sp. z o.o. | Masovian |
| SunSoft | Silesian |
| Suntech S.A. | Masovian |
| Superhot | |
| Supermedia Sp. z o.o. | Masovian |
| SuperMemo World Sp. z o.o. | Greater Poland |
| Superskrypt Sp. z o.o. sp. k. | |
| Support.pl Sp. z o.o. | Masovian |
| Supremo Sp. z o.o. | Greater Poland |
| Supremum SEO Sp. z o.o. | |
| Surfer Sp. z o.o. | |
| Surg-Tech Sp. z o.o. Sp. komandytowa | |
| Surprise.Design | Silesian |
| Surveily Sp. z o.o. | |
| Suwary S.A. | |
| ĹwidMAN S.C. | Lublin |
| Swift Apps Sp. z o.o. | |
| Swing Development Sp. z o.o. | Masovian |
| SWITSYS Information Technology | |
| SWPL Sp. z o.o. | |
| Syften | |
| Sygeon | |
| Sygnisoft Sp. z o.o. | |
| Sygnity S.A. | |
| Sykom | Subcarpathian |
| Sylius | |
| Symetria | Greater Poland |
| Synappse | |