| Level 13 Communications | Gauteng |
| Level Finance | |
| LevelZero Communications | Western Cape |
| LexisNexis South Africa | Western Cape |
| Lexpro Systems Pty Ltd | Gauteng |
| Libwin Library Systems CC | Gauteng |
| Limabean | Western Cape |
| Lime Green Digital (Pty) Ltd | |
| LimeHouse | Western Cape |
| Limenco Design | Gauteng |
| Limestone Residential Properties | Gauteng |
| Limtech | Gauteng |
| Linc | Western Cape |
| Linkable Analytics | |
| Linkfields Innovations (Pty) Ltd | |
| Linux Warehouse | Gauteng |
| Linuxweb | Gauteng |
| Linx | |
| Liorra Tech (Pty) Ltd | |
| Lipa Payments | Western Cape |
| Liquid Thought | Western Cape |
| LIT Creations | Gauteng |
| Livemon | KwaZulu-Natal |
| Livesurf | Western Cape |
| Lizzard Webdesign | |
| Logical Wireless | Gauteng |
| LogicSMS | Gauteng |
| Logitech SA | Gauteng |
| Logix Design and Development CC | KwaZulu-Natal |
| LooksGood Design Studio | KwaZulu-Natal |
| Lorge Consulting Services (Pty) Ltd | Gauteng |
| Low Cost WebDesign | Free State |
| Lucid Ocean | Western Cape |
| Luco Audio Electronics CC | KwaZulu-Natal |
| Lula Loop (Pty) Ltd | |
| Lulalend | |
| LVC Data Recovery | Gauteng |
| Lwazi Telecommunications CC | Gauteng |
| M&C Saatchi | Western Cape |
| MacWorks | Gauteng |
| Madberry Studio | Gauteng |
| Magix Security | Gauteng |
| Mahube Turn-Key Solutions (Pty) Ltd | Gauteng |
| Mama Money | Western Cape |
| Man3000 (Pty) Ltd | Gauteng |
| Management Planing Systems | Gauteng |
| MANCOSA | |
| Manuton Computer Care | Gauteng |
| Marais Software Solutions (Pty) Ltd | Gauteng |
| Marchant Capital | |