| QPS Digital | |
| QPS Photonics, Inc. | Quebec |
| QRX Technology Group | Ontario |
| QScale | |
| QSciTech | Quebec |
| QSI | Ontario |
| QSound Labs, Inc. | Alberta |
| Qstrat | Ontario |
| QSX Software Group | British Columbia |
| QT Web Designs | Ontario |
| QTECH Hybrid Systems, Inc. | Ontario |
| Qtility Software Ltd | Alberta |
| Qu Biologics, Inc. | |
| Quad Source Canada, Inc. | Ontario |
| Quadra Systems | Ontario |
| QuadraKnowledge | Quebec |
| Quadrant Electronics, Inc. | |
| Quadrant Newmedia Corporation | Saskatchewan |
| Quadrant Productions | Ontario |
| Quadrillion Corporation | Ontario |
| Quadro Communications Co-operative, Inc. | Ontario |
| Quadro Engineering | |
| Quadro Liquids | |
| Quadrumane Technologies | Quebec |
| Quaero | |
| Quaero, Inc. | |
| Qualia Designs | British Columbia |
| Qualicode Logiciel | Quebec |
| Qualicom Innovations, Inc. | Ontario |
| Qualiqua | Quebec |
| Qualitative Business Systems | British Columbia |
| qualiTEAS | |
| QualiTech | Quebec |
| Qualitech Services Informatiques | |
| Qualitiqua | |
| Quality Computing Works | Ontario |
| Quality Integrators Corporation | Ontario |
| Quality Technology Solutions | Alberta |
| Quality Workforce | Ontario |
| QualityGPTs | |
| Qualpro Management, Inc. | Ontario |
| Quandri | |
| Quanser | Ontario |
| Quantacet | |
| Quantara Corporation | British Columbia |
| Quantech Software.com, Inc. | British Columbia |
| Quantics Software, Inc. | |
| Quantifi | |
| Quantilytics | |
| Quantino | Quebec |