| Rackel Creative | British Columbia |
| RackNine, Inc. | Alberta |
| RAD AI | Ontario |
| RAD International Ltd | Ontario |
| Rada Technologie | |
| Radar Hill | British Columbia |
| Radial Games Corporation | |
| Radialis, Inc. | |
| Radiant | Ontario |
| Radiant Biotherapeutics | |
| Radiant Biotherapeutics | |
| Radiant Communications Corporation | British Columbia |
| Radical Electronics | Saskatchewan |
| Radical I/O Technology | British Columbia |
| Radical Ventures | Ontario |
| Radical VR | Ontario |
| Radicle | Alberta |
| Radio IP Software | Quebec |
| Radio Solution | Quebec |
| Radio Talbot | Quebec |
| Radioactif | Quebec |
| Radioworld | Ontario |
| Radish Networks | Saskatchewan |
| Radium, Inc. | Quebec |
| Radius SFU | |
| Radius Works | Ontario |
| Radom Data API | |
| Rae Media, Inc. | British Columbia |
| Raedwulf Space and Defence, Inc. | Ontario |
| Raesgo Creative | Ontario |
| Rafiki Technologies, Inc. | Alberta |
| RaftingMédia | Quebec |
| RAGE Software | Ontario |
| RageCure Games | |
| Ragworks.AI Ltd | |
| Rahi Software | |
| Raidog Solutions Computer Consulting | British Columbia |
| Rain | |
| Rainbow Computers | Ontario |
| Rainfall Software | |
| Rainforest Alberta | Alberta |
| Rainforest Automation | |
| Rainmaker Leads | Ontario |
| Rainy Town Media | |
| Raiven Capital | |
| Raize Digital | |
| Raja Sandhu | Ontario |
| Rakovina Therapeutics, Inc. | |
| Rakr | |
| Ralcomm Ltd | Alberta |