| Ready2Launch | Nova Scotia |
| Readymode | |
| REAI | Quebec |
| Real Digital | Ontario |
| Real Estate Webmasters | British Columbia |
| REAL HR | |
| Real Life Robotics, Inc. | |
| Real Matters | Ontario |
| Real Profit Solutions, Inc. | British Columbia |
| REAL Recruitment | |
| Real Ventures | Quebec |
| RealDecoy, Inc. | Ontario |
| Realisys, Inc. | Quebec |
| RealIT Management, Inc. | Ontario |
| Reality Bytes, Inc. | Alberta |
| Reality Information Services | Quebec |
| Reality Software, Inc. | Ontario |
| Realize Strategies | |
| Really Good Solutions | |
| reallyActive | Quebec |
| RealPageMaker | Alberta |
| RealPython | British Columbia |
| RealSpace Vision Communication, Inc. | British Columbia |
| RealTech Solutions | British Columbia |
| Realtime 7, Inc. | Ontario |
| RealTime Technology Group, Inc. | Ontario |
| RealtyNinja Services Ltd | British Columbia |
| Reasoning and Learning Lab | Quebec |
| Reaxion Graphics | |
| Reazent | |
| Rebel Networks | Ontario |
| Rebel Trail Web & Mobile Solutions | Ontario |
| Rebel.com | Ontario |
| reBOOT Peterborough | Ontario |
| ReBrand Advertising+Design, Inc. | Ontario |
| Rebus Community | |
| RecallMax | |
| Receptiviti, Inc. | |
| ReCharged | |
| Recollective | Ontario |
| Recollective Consulting, Inc. | |
| Recollective, Inc. | |
| Recon Creative Design | Newfoundland and Labrador |
| Reconfigure.ca | Ontario |
| RecoverMyPc, Inc. | Ontario |
| Recovery Force | Ontario |
| RECreativ | |
| Recruiter.ca | Ontario |
| Recruitment Partners, Inc. | |
| Recrutement Technologique Quantum | Quebec |