| SOC Informatique | Bas-Rhin |
| Social Transport Solutions | |
| SocialCompare S.A.R.L. | Var |
| Socialyse Paris | |
| Sociel | Loire |
| Société ADCI | Marne |
| Société Française de Bioinformatique | |
| Société informatique de France | Essonne |
| Société Téléphonie Bordelaise Duplantier | Lot-et-Garonne |
| Socimet | Côte-d'Or |
| Socram Branque | |
| SodeaSoft | Pas-de-Calais |
| SoFAB | Alpes-Maritimes |
| SOFALI | |
| Sofft Industrie | Métropole de Lyon |
| Sofft Technologies | Métropole de Lyon |
| Sofialys | Seine-Maritime |
| Sofracs | Paris |
| Sofrecom | Val-de-Marne |
| Soft Concept | Métropole de Lyon |
| Soft-Lan Informatique | Indre |
| Softbuilder | |
| Softeam | Paris |
| Softeam Agency | Paris |
| SoftFluent | |
| Softing | Yvelines |
| Softinnov | |
| Softlaw S.A.S. | Paris |
| Softouest | Loire-Atlantique |
| Softthinks S.A.S. | |
| Software Attitude | Seine-et-Marne |
| Software Domain | Loire-Atlantique |
| Software Heritage | |
| Sogelink | Métropole de Lyon |
| Sogeti | Hauts-de-Seine |
| Sogetrel | Hauts-de-Seine |
| Soitec | Isère |
| Soladis Group | |
| Solean | |
| Soledge | |
| Soledis | Morbihan |
| SolicITeam | Bouches-du-Rhône |
| Solidpepper | Pyrénées-Atlantiques |
| Solidshield | Alpes-Maritimes |
| Solis System | Gard |
| Sollan | Hauts-de-Seine |
| SoloLearn | |
| Solstys | Côtes-d'Armor |
| Solsys Informatique | Val-d'Oise |
| Soluce Informatique Pornic | Loire-Atlantique |