| Patricio Comunicación | |
| PCTEK | Montevideo |
| Pento | Montevideo |
| Perceptiva Tech | |
| Pinky | |
| Pixeina | Montevideo |
| Pixel Dreams | |
| Pixelina | Montevideo |
| Posición Digital | |
| Power Systems S.R.L. | Montevideo |
| PowerStreet | Montevideo |
| Press Start Evolution | |
| PRNET Software | Montevideo |
| PRO International | Montevideo |
| Procodata S.A. | Montevideo |
| Proinfo | Montevideo |
| ProRed | Montevideo |
| Prosis | Montevideo |
| Publicidad Web | Montevideo |
| Punta del Este Flight School | |
| PuntoExe Consultants | Montevideo |
| Pyxis | Montevideo |
| Pyxis.tech | |
| QAlified | Montevideo |
| QB Media | Montevideo |
| Qualabs | |
| Qualy IT | Montevideo |
| Quanam | Montevideo |
| Quantum Latino | Montevideo |
| Quantum-South | Montevideo |
| Rabbit - Incubadora de Hardware | Montevideo |
| Radical Online | |
| Red Académica Uruguaya | Montevideo |
| Red21.com | Montevideo |
| RedCLARA | Montevideo |
| REDDevs | |
| Redex Sistemas | Montevideo |
| Rednet21 | Montevideo |
| RUEVAL, S.A. | Canelones |
| S&A IT Solutions | Montevideo |
| Sagant | |
| Saico | Montevideo |
| San Diego SoftWorks | Montevideo |
| Satellogic | |
| Security Advisor | Montevideo |
| Seglico | Montevideo |
| Semana de la Ciencia y la Tecnologia | |
| Senda | Montevideo |
| SensorData | |
| SeoWilko | |