| Simply Wall Street Pty Ltd | New South Wales |
| simPRO Group Pty Ltd | Queensland |
| Singtel Optus Pty Ltd | New South Wales |
| Sinorbis Australia Pty Ltd | |
| SIS Industrial Cyber Security | Victoria |
| Sitback Solutions | New South Wales |
| Sitecentre Pty Ltd | |
| Sitelabs | Victoria |
| SiteMinder | New South Wales |
| SiteOptiq | |
| SitePoint Pty Ltd | Victoria |
| Sites n Stores | Victoria |
| SiteSuite Website Design | New South Wales |
| SiteZero | Queensland |
| SK8Tech | New South Wales |
| Skalata Ventures Pty Ltd | |
| Skandus Pty Ltd | New South Wales |
| SKD Software House | |
| Sked Social | Victoria |
| SkedGo | New South Wales |
| Sketch That | Victoria |
| Skin2Neuron Pty Ltd | |
| Skip Capital | New South Wales |
| Skript, Inc. | New South Wales |
| SKS Indigenous Technologies | |
| Sky and Space Company Ltd | Western Australia |
| Sky High Digital | |
| Skyfii Ltd | New South Wales |
| Skyline Systems | |
| SkyNet Satellite Communications Pty Ltd | Queensland |
| Skyward Digital | |
| Slant Digital Pty Ltd | |
| Slickfish | Western Australia |
| Slingshot Accelerator Pty Ltd | New South Wales |
| Slinky | |
| Slinky Creative | Western Australia |
| Slinky Interactive Media | |
| Slinky Web Design | Western Australia |
| Slinky Web Hosting | Western Australia |
| Slyp Pty Ltd | New South Wales |
| Small Business Web Designs | New South Wales |
| Small Multiples Pty Ltd | |
| smallbiz Web Design | |
| Smart Artist Internet Pty Ltd | New South Wales |
| Smart Company Software | |
| Smart Foods Consulting Pty Ltd | New South Wales |
| Smart SEO | |
| Smart Token Labs | New South Wales |
| Smart Traffic Pty Ltd | New South Wales |
| Smart Voice | Victoria |