| PCDomino.com | Tamaulipas |
| PCEL | Mexico City |
| Pcounter México | Mexico City |
| Pcredcom | Nuevo León |
| PCWorld México | Mexico City |
| Pepper Technologies México | Mexico City |
| Perfect Choice | Jalisco |
| Persto | Mexico City |
| Pice-Software | Jalisco |
| Pisicionart | Querétaro |
| Pix2Byte | Puebla |
| Pixan | Jalisco |
| Pixela | Mexico City |
| Pixelmedia | Mexico City |
| Pixzelle Studio | |
| Planetaweb | Mexico City |
| PlanetMedia | |
| Plataforma Abierta de Innovación | Mexico City |
| Play Business, S.A.P.I. de C.V. | |
| Plazanetwork | Mexico City |
| Pocket de Latinoamérica, S.A.P.I. de C.V. | Mexico City |
| PoderNet | Mexico City |
| Polígono Capital | Jalisco |
| Pragmatec | |
| Praxis | Mexico City |
| Preparatoria CUAM | |
| Prexto Financial, S.A.P.I. de C.V. | |
| Productos Soluciones y Servicio, S.A. de C.V. | Mexico City |
| Programatica Creativa | Mexico City |
| Promecap, S.A. de C.V. | Mexico City |
| Promotech México, S.A. de C.V. | Mexico City |
| Promoweb | Mexico City |
| ProTecnia | Mexico City |
| Proveedores de Facturación Electrónica y Software, S.A. de C.V. | State of Mexico |
| Proyecto:pixel | Mexico City |
| Proyectos y Conferencias S.A. de C.V. | Mexico City |
| Publi-K2 | Mexico City |
| Publico | Mexico City |
| Publitotal | Nuevo León |
| Puerto Vallarta's Technology Solution | Jalisco |
| PUNK Solutions, S.A. de C.V. | Quintana Roo |
| Punto Blu | Mexico City |
| Punto Commerce | Jalisco |
| Punto Coworking | Mexico City |
| PV Comunicaciones, S.A. de C.V. | Chihuahua |
| PYV Tecnologia | Mexico City |
| Q-Soft México, S.A. de C.V. | Chihuahua |
| Qbit Mexhico | Mexico City |
| Quadrantix | Baja California |
| Quadrato | Mexico City |