| Qwerty B.V. | North Brabant |
| Qwezz B.V. | Limburg |
| R&R Automatisering & Oplossingen | |
| R.E.D. Systemen B.V. | South Holland |
| R2 retail solutions B.V. | Limburg |
| Rabión Consultancy | South Holland |
| Rabobank | Utrecht |
| Rabobank | |
| Racer | North Holland |
| Radboud Universiteit | Gelderland |
| Radboud Universiteit - Institute for Computing and Information Sciences | Gelderland |
| Radboud Universiteit - Wiskunde | Gelderland |
| Radboud Universiteit Nijmegen - Faculteit der Natuurwetenschappen, Wiskunde en Informatica | Gelderland |
| Radboud University - Institute for Computing and Information Sciences | |
| Radio Zeeland DMP | Zeeland |
| RAID Recovery Service | North Brabant |
| Rainbow Solutions B.V. | Gelderland |
| Raito B.V. | |
| RAM Infotechnology | Utrecht |
| RAM Mobile Data B.V. | Utrecht |
| Randstad N.V. | North Holland |
| Ranj | South Holland |
| Raster | Gelderland |
| RDM Makerspace | |
| Re-Order-It | Utrecht |
| Re:ason Digital Empowerment | South Holland |
| Reach Digital | |
| React Summit | North Holland |
| RealHosting | North Holland |
| RealSolution | |
| Realtime Register B.V. | Overijssel |
| Realworld Systems B.V. | Gelderland |
| ReCheck B.V. | Limburg |
| Recommendme | |
| Recrout | North Holland |
| Recruitee.com | North Holland |
| RecruitmentTechnologies | North Holland |
| Red Data | |
| Red Kubes B.V. | |
| Red Star Electronics B.V. | South Holland |
| Redakt B.V. | |
| Redevco B.V. | |
| Redhound Internetbureau | Overijssel |
| Redkiwi | South Holland |
| Redkiwi | |
| RedMedTech Discovery Fund | Gelderland |
| RedVan Solution B.V. | |
| Reflecta Automation B.V. | South Holland |
| Reflex Online | Gelderland |
| Registratie.nl | Gelderland |