| M-Soft, spol. s r.o. | |
| Machine Learning Prague | Prague |
| Macom Security, spol. s r.o. | |
| MacroToolworks.com | Hradec Králové |
| MACROWARE, s.r.o. | South Moravian |
| Mader.cz | Liberec |
| Madesense.digital, s.r.o. | Prague |
| MADFINGER Games, a.s. | |
| Magmio, a.s. | |
| MAIT | |
| Make | |
| makeITtoday | |
| MakersLab | Prague |
| MamutNet, s.r.o. | South Moravian |
| Manifesto | |
| Mapfactor | Prague |
| MapleTop Software | Prague |
| Mapotic, s.r.o. | |
| MAPS HK, s.r.o. | Hradec Králové |
| MARaCO, spol. s r.o. | Central Bohemian |
| Marek Hnátek | South Moravian |
| Marek Rosa | Prague |
| Marek Vidtman | Plzeň |
| Marketup | Prague |
| Markus Technology, s.r.o. | |
| Martin Hinner | Prague |
| Martin Šimko | South Moravian |
| Masaryk University - Department of Mathematics and Statistics | South Moravian |
| Masarykova univerzita - Faculty of Informatics | South Moravian |
| Mascat.cz | South Bohemian |
| Matematika pro každého | Prague |
| Maxima pojišťovna, a.s. | |
| MB Data | Prague |
| mBank ČR | Prague |
| MDA Capital Invest, a.s. | |
| Media Expert, s.r.o. | Prague |
| Media Platform, s.r.o. | |
| MEDIAFABRÍCA, s.r.o. | Moravian-Silesian |
| MEDIATEL, spol. s r.o. | Prague |
| Medicem Group, a.s. | |
| Mediware, a.s. | |
| Meetnlearn, s.r.o. | |
| MEMOS Software, s.r.o. | Prague |
| Meta IT, s.r.o. | |
| Metropolitní univerzita Praha, o.p.s. | Prague |
| Meyer - Software - Application | South Bohemian |
| mForce | |
| MGE Data | |
| MHM Computer, a.s. | Prague |
| MIA Studio, spol. s r.o. | Prague |